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Newswise — INDIANAPOLIS — Indiana University School of Medicine scientists have developed a powerful new imaging technique to study bone marrow in mouse models. By overcoming key challenges unique to imaging this complex tissue, this advancement could support future drug development and therapies for conditions involving bone marrow, including cancers, autoimmune diseases and musculoskeletal disorders….
Newswise — PHILADELPHIA — (April 14, 2025) —The Wistar Institute’s Joseph Salvino, Ph.D., — in collaboration with Elton Zeqiraj, Ph.D., of The University of Leeds and Roger Greenberg, M.D., Ph.D., of The Perelman School of Medicine at the University of Pennsylvania — has discovered a type of “molecular glue” that can be used to inhibit…
Newswise — Researchers are studying messenger RNA’s potential to treat and prevent an array of serious conditions—including cancer. In a briefing for journalists by Johns Hopkins University and Medicine, mRNA researchers will offer broad perspective on the history and development of this technology and discuss its future promise as the foundation for treatments for conditions…
Newswise — Parents of children who have been diagnosed with multiple sclerosis likely have many questions about their child’s condition. Receiving a diagnosis can be overwhelming and searching for information online can turn up complicated explanations. Laura Saucier, MD, MSc, a neuroimmunologist in the Neurological Institute at Children’s Hospital Los Angeles, breaks down the key…
Newswise — Autoimmune diseases, which are estimated to affect more than 15 million people in the U.S., occur when the body responds to immune-system false alarms, and infection-fighting first responders are sent out to attack threats that aren’t there. Scientists have long understood how the false alarms get triggered, but the second step of dispatching…
Newswise — Protein kinase research presents an opportunity to explore molecular targets in the body to treat diseases like cancer and autoimmune disorders. These enzymes have the potential to bind to cellular sites and inhibit dysfunctional behavior, such as the overproduction of cancerous cells and tumor formation. With the vast combination of possible kinase and…
Newswise — Two new studies led by researchers at Hospital for Special Surgery (HSS) have uncovered key biological mechanisms driving systemic sclerosis (SSc), or scleroderma – a rare and often devastating autoimmune disease that causes fibrosis (tissue hardening) and inflammation. The research, published in the March issue of the Journal of Experimental Medicine, helps explain…
Newswise — PHOENIX — Pesquisadores da Mayo Clinic identificaram uma terapia direcionada que pode trazer alívio para as pessoas que vivem com líquen plano, uma condição inflamatória crônica da pele, cabelo, unhas, boca e genitais. Eles descreveram suas descobertas em um estudo publicado no Journal of Clinical Investigation, relatando seu primeiro ensaio clínico em humanos, fase 2….
Newswise — HOUSTON-(Jan. 21, 2025) – Houston Methodist researchers have identified a key protein as a potential therapeutic target for stopping the body’s immune system from mistakenly attacking itself, offering new hope for treating autoimmune diseases and allergies. The paper titled “Apex1 safeguards genomic stability to ensure a cytopathic T cell fate in autoimmune disease…
