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Newswise — When we think of type 2 diabetes, images of heart problems or kidney damage often come to mind. But lurking quietly behind these well-known complications is another serious threat—bone disease. Affecting over 90% of global diabetes cases, type 2 diabetes doesn’t just compromise vital organs; it takes a hidden toll on the skeleton,…
Newswise — Citrus plants, traditionally cultivated in tropical and subtropical climates, are highly vulnerable to cold stress, which can drastically affect both yield and fruit quality. With climate change triggering more frequent and intense cold spells, the demand for citrus varieties that can withstand these conditions has never been more pressing. Although previous studies have…
Newswise — ST. LOUIS, MO, March 5, 2025 — A research team led by Andrea Eveland, PhD, associate member at the Donald Danforth Plant Science Center, has uncovered key genetic regulatory factors that control pleiotropy—a phenomenon where a single gene influences multiple traits. Their study, “Regulatory variation controlling architectural pleiotropy” recently published in the journal,…
Newswise — LOS ANGELES (Feb. 20, 2025) — Ze’ev Ronai, PhD, a prominent cancer investigator and director of the Translational Research Institute at Cedars-Sinai, has received an Outstanding Investigator Award from the National Cancer Institute. This is the second time that Ronai has collected the award, which supports cancer researchers working on biomedical, clinical and behavioral…
Newswise — Frostbite is a severe cold injury that affects millions worldwide, often resulting in prolonged recovery, scarring, and long-term complications such as chronic pain and dysfunction. The injury typically begins with cold-induced cell death, localized inflammation, and tissue ischemia, which disrupt the skin’s ability to heal. Current therapies, such as calcium channel blockers, function…
Newswise — Terpenoids are a diverse and essential group of natural products produced by plants, playing key roles in defense, communication, and hormone regulation. Their biosynthesis begins with prototypical plant terpene synthases (TPSs), enzymes believed to have evolved from a fusion of bacterial diterpene cyclases (DTCs) and terpene synthases (TSs). Despite this hypothesis, the origin…
Newswise — Rare Disease Day is observed on February 28 each year, or February 29th on leap years — the rarest day on the calendar. It is a day dedicated to raising awareness about rare diseases and advocating for health equity to ensure all people living with rare diseases have access to diagnosis and therapies….
Newswise — Cucumbers, one of the world’s most widely grown crops, face a significant challenge in regions with cold climates, particularly in winter cultivation within solar greenhouses. Cold stress negatively affects their growth, yield, and overall quality. While grafting onto cold-resistant rootstocks has proven effective in improving stress tolerance, the precise molecular mechanisms behind graft-induced…
Newswise — Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell’s nuclear membrane. The findings, by a University of Pittsburgh team using the Bridges-2 system at the Pittsburgh Supercomputing Center, suggest how the capsid may deform to fit…
Newswise — Kansas is experiencing one of the largest tuberculosis outbreaks in U.S. history after 67 cases of active TB were confirmed as of Jan. 24. Researcher Tony Hu, the Weatherhead Presidential Chair in Biotechnology Innovation at Tulane University School of Medicine, said the outbreak highlights the need for more vigorous public health surveillance for…
