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Newswise — Bone regeneration is a multifaceted process involving the well-coordinated interaction of cellular functions such as the regulation of inflammation, the formation of new blood vessels, and the development of bone tissue. Bone regeneration is a multifaceted process involving the well-coordinated interplay of multiple cellular activities, such as inflammation control, blood vessel and bone…
Newswise — Sepsis, a severe and often fatal complication of infection, is a leading cause of both ALI and acute respiratory distress syndrome (ARDS). These conditions, which are associated with high mortality rates, remain challenging to treat due to the lack of effective therapies. NETs play a central role in the progression of sepsis, as…
BACKGROUND Newswise — Heart transplantation is a crucial intervention for severe heart failure, yet the challenge of organ rejection is significant. Bone marrow mesenchymal stem cells (BMSCs) and their exosomes have demonstrated potential in modulating T cells, dendtitic cells (DCs), and cytokines to achieve immunomodulatory effects. DCs, as key antigen-presenting cells, play a critical role…
Newswise — Researchers describe a new potential role for Oleanolic Acid as a modulator of the DNA damage response following Camptothecin treatment. Administration of Oleanolic Acid in combination with Camptothecin for cancer chemotherapy may reduce the amount of drug needed and increase the effectiveness of treatment. The findings are part of a novel research program…
Newswise — This article discusses the interplay between colorectal cancer (CRC) stem cells, tumor microenvironment (TME), and gut microbiota, emphasizing their dynamic roles in cancer progression and treatment resistance. It highlights the adaptability of CRC stem cells, the bidirectional influence of TME, and the multifaceted impact of gut microbiota on CRC. The manuscript proposes innovative…
Newswise — Four-and-a-half hours; the equivalent of a drive from Las Vegas to Los Angeles, assuming traffic isn’t log jammed on Interstate 15. This is the critical window of time for stroke victims to be eligible for treatment at the hospital after a stroke begins to affect the brain. Within this tight window, a patient…
Newswise — For years, Université de Montréal medical professor Stephanie Fulton and her team have been unravelling the mechanisms in the human nervous system that control people’s need to eat and to engage in physical activity, and how their metabolism affects their mood. Their latest discovery, published in Nature Communications, takes that knowledge a step…
Newswise — For years, glucose-sensitive membranes have been a key focus for improving controlled insulin release in diabetes treatments. Glucose-sensitive membrane was previously constructed using glucose oxidase (GOD)-based glucose-sensitive materials. GOD-based systems suffer from limited oxygen supply and inactivation by hydrogen peroxide. Phenylboronic acid (PBA), well-known glucose reporter, exhibits higher reliability compared with GOD. Unfortunately,…
Newswise — PLYMOUTH MEETING, PA [December 4, 2024] — The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) today announced the awarding of new quality improvement research grants aimed at advancing care for patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL). The NCCN ORP will oversee these projects, with funding provided through support from…
Newswise — CLEVELAND, Dec. 19, 2024 — GenomOncology is proud to announce the appointment of Dr. Jonathan “Jack” Lord, M.D., to its Board of Directors. A nationally recognized leader in healthcare innovation, Dr. Lord brings a wealth of expertise in driving change through new technologies and therapies, making him an ideal fit for GenomOncology’s mission to…
