March 12, 2025

Digestive Disorders

Adiso Therapeutics Announces Data Publication of Two Phase 1 Studies of First-in-Class Neutrophil Modulator ADS051 in the American Journal of Gastroenterology | Newswise

Adiso Therapeutics Announces Data Publication of Two Phase 1 Studies of First-in-Class Neutrophil Modulator ADS051 in the American Journal of Gastroenterology | Newswise

David Bale010 mins

Newswise — CONCORD, Mass., March 6, 2025 /PRNewswire/ — Adiso Therapeutics, Inc. announced the publication of the results of two Phase 1 studies, which showed that healthy subjects and ulcerative colitis (UC) patients given oral doses of ADS051, a novel modulator of neutrophils being developed for Inflammatory Bowel Disease (IBD), could be safely administered and well-tolerated in…

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NCCN Announces New Gastrointestinal Cancer Research Grants in Collaboration with Taiho Oncology, Inc. | Newswise

NCCN Announces New Gastrointestinal Cancer Research Grants in Collaboration with Taiho Oncology, Inc. | Newswise

David Bale06 mins

Newswise — PLYMOUTH MEETING, PA [February 25, 2025] — The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) today announced new funding aimed at advancing clinical research in gastrointestinal cancers. Three grants have been awarded to innovative investigator-initiated research to explore the potential of tipiracil/trifluridine (FTD/TPI) and/or futibatinib in treating gastrointestinal cancers. The initiative…

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UCLA to Lead .6M NIH-Funded Center to Unlock the Role of Viruses in Human Health | Newswise

UCLA to Lead $20.6M NIH-Funded Center to Unlock the Role of Viruses in Human Health | Newswise

David Bale011 mins

Newswise — The National Institutes of Health has awarded a $20.6 million grant over five years to establish one of five Human Virome Characterization Centers, or HVCCs, leveraging UCLA leadership and the collective expertise of interdisciplinary scientists nationwide to advance understanding of the virome’s role in human health and disease across the oral-gut-brain axis. Yvonne…

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ACG-ASGE Quality Indicators for Upper GI Endoscopy and More in the February Issue of AJG | Newswise

ACG-ASGE Quality Indicators for Upper GI Endoscopy and More in the February Issue of AJG | Newswise

David Bale04 mins

Newswise — The February issue of The American Journal of Gastroenterology highlights new clinical science and reviews, including joint ACG-ASGE quality indicators for upper GI endoscopy, the first medication for the treatment of at-risk metabolic-associated steatohepatitis (MASH), and a digital gut-directed hypnotherapy program for irritable bowel syndrome (IBS). This month we also published articles on…

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UCLA to Lead .6M NIH-Funded Center to Unlock the Role of Viruses in Human Health | Newswise

Blood Test Could Guide Use of Anti-Inflammatory Drug Celecoxib to Reduce Risk of Colon Cancer Recurrence | Newswise

David Bale07 mins

Newswise — Boston – A data analysis from a randomized clinical trial for stage 3 colon cancer patients by investigators at Dana-Farber Brigham Cancer Center found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit from adding of celecoxib, to post surgery treatment. The analysis showed…

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UCLA to Lead .6M NIH-Funded Center to Unlock the Role of Viruses in Human Health | Newswise

Interplay and Therapeutic Implications of Colorect | Newswise

David Bale02 mins

Newswise — This article discusses the interplay between colorectal cancer (CRC) stem cells, tumor microenvironment (TME), and gut microbiota, emphasizing their dynamic roles in cancer progression and treatment resistance. It highlights the adaptability of CRC stem cells, the bidirectional influence of TME, and the multifaceted impact of gut microbiota on CRC. The manuscript proposes innovative…

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UCLA to Lead .6M NIH-Funded Center to Unlock the Role of Viruses in Human Health | Newswise

Predictive Modeling Addresses Healthcare Dispariti | Newswise

David Bale07 mins

Newswise — Cleveland Clinic developed a predictive model to identify patients at risk of developing gastric (stomach) cancer who may benefit from stomach cancer screening. The model is designed to identify who might need regular upper endoscopies to screen for stomach cancer. Although U.S. patients get routinely screened for other diseases, endoscopies – where a patient needs anesthesia – are…

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