Mayo Clinic’s largest-ever exome study offers bl | Newswise

Mayo Clinic’s largest-ever exome study offers bl | Newswise

ROCHESTER, Minn. — Mayo Clinic’s Center for Individualized Medicine has achieved a significant milestone with its Tapestry study, generating the clinic’s largest-ever collection of exome data, which include genes that code for proteins — key to understanding health and disease.   Led by Konstantinos Lazaridis, M.D., the study analyzed DNA from over 100,000 participants from diverse backgrounds, providing important insights into…

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Mayo Clinic’s largest-ever exome study offers bl | Newswise

PCORI commits $156 million to new patient-centered | Newswise

Newswise — WASHINGTON, Dec. 3, 2024 /PRNewswire/ — The Patient-Centered Outcomes Research Institute (PCORI) has approved funding awards totaling more than $156 million for new patient-centered comparative clinical effectiveness research (CER), as well as research to improve methods and strengthen the science of engagement in CER. The awards will support 13 CER studies, including three…

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Twice-yearly lenacapavir for PrEP reduces HIV infections by 96% | Newswise

Twice-yearly lenacapavir for PrEP reduces HIV infections by 96% | Newswise

Twice-yearly injections of the capsid inhibitor drug lenacapavir can prevent the vast majority of HIV infections, according to a Phase 3 clinical trial published Wednesday in the New England Journal of Medicine. HIV pre-exposure prophylaxis (PrEP) has emerged as a crucial tool for fighting the global HIV epidemic, but researchers say daily pill regimens remain an obstacle…

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Parkinson’s drug changes the gut microbiome for the worse due to iron deficiency | Newswise

Parkinson’s drug changes the gut microbiome for the worse due to iron deficiency | Newswise

In a groundbreaking new study, conducted within the framework of the FWF-funded Cluster of Excellence “Microbiomes drive Planetary Health”, scientists from the University of Vienna, in collaboration with the University of Southampton, Aalborg University and Boston University, have revealed that the widely prescribed Parkinson’s disease drug entacapone significantly disrupts the human gut microbiome by inducing…

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Implementing ancient agricultural practices to con | Newswise

Implementing ancient agricultural practices to con | Newswise

As global water resources become more strained, the insights gained from traditional agricultural systems could pave the way for the development of innovative, low-water-use agricultural practices to confront the growing challenges of water scarcity and food insecurity in arid and marginal regions. A new study exploring traditional sunken groundwater-harvesting agroecosystems in coastal and inland sand…

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